Prolific Machines

Prolific Machines develops a Photomolecular™ cell line development platform that uses optogenetics and AI-driven bioprocess optimization to make difficult protein production simpler and more scalable. By using light to precisely control transcription, secretion pathways, and post‑translational modification genes, the platform can boost titers (up to ~5× reported) and enable expression of hard-to-produce biotherapeutics while improving product quality and consistency. Their solutions are designed for flexibility across development and manufacturing contexts and include collaboration and technical support to integrate into customers’ workflows.