Manifold Bio
Manifold Bio is developing AI models for protein therapeutic design using proprietary experimental data. They focus on high-throughput protein engineering combined with computational design to create biologics, with a team specialized in protein engineering, biology, and computational sciences.
Manifold Bio is a biotech company that designs tissue-targeted medicines directly in vivo. They built a high-throughput in vivo (HTV) discovery engine that combines massively multiplexed in‑animal screening with AI‑powered design to discover and optimize targeted biologics. The platform enables engineering of tissue- and cell-type‑specific delivery modalities (for example, next‑generation brain shuttles) and supports strategic partnerships with pharma. Their approach aims to accelerate discovery and increase translational success for targeted biologic therapeutics.
Roche signs $2B pact to pilot Manifold Bio's shuttles to the brain
Nov 3, 2025
Manifold Bio Expands Leadership Team to Drive its AI + In Vivo Targeted Biologics Platform
Dec 16, 2025
Manifold Bio Expands Leadership Team to Drive its AI + In Vivo Targeted Biologics Platform
Dec 15, 2025
Headquarters
San Francisco, CA
Company Size
201-500 employees
Founded
2018
Industry
Technology
Glassdoor Rating
4.2 / 5
Sarah Johnson
Chief Executive Officer
Michael Chen
Chief Technology Officer
Emily Williams
VP of Engineering
David Rodriguez
VP of Product
Jessica Thompson
Chief Financial Officer
Andrew Park
VP of Sales
View leadership team, funding history,
and employee contacts for Manifold Bio.
Manifold Bio didn’t post a salary, so this is our estimate from similar listings.
Roche taps an AI specialist to craft new brain drugs
Nov 3, 2025
Senior Scientist – Protein Design
AstraZeneca
Scientist - AI & ML for Protein and Antibody Engineering
Roche
Senior scientist translation research – AI Protein Structure & Design
VIB
Senior Data Scientist - Protein Structure ML models
Amgen
Senior Scientist of Protein Sciences
Strand Therapeutics
Computational Protein Design Scientist
LLNL