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Associate Scientist I, Biochemistry at Pliant Therapeutics, Inc. - ApplyBlast

Associate Scientist I, Biochemistry

Pliant Therapeutics, Inc.

2 days ago

South San Francisco, California, United States

Onsite

Full Time

Junior

0 applicants

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About this role

The Associate Scientist I, Biochemistry role at Pliant involves developing, optimizing, and running biochemical binding assays to screen compounds in medium- to high-throughput formats. This hands-on laboratory position focuses on AlphaScreen/AlphaLISA assays, generating potency and selectivity data to guide medicinal chemistry decisions. The role requires expertise in assay development, high-throughput screening, and data analysis to support hit identification and structure-activity relationship (SAR) studies.

Responsibilities

Design and optimize biochemical binding assays using AlphaScreen and AlphaLISA formats
Execute medium- to high-throughput screening campaigns and dose-response profiling
Analyze and report data using Scilligence and maintain electronic lab notebook records

Skills

Qualifications

BS in BiochemistryBS in BiologyBS in ChemistryMS in BiochemistryMS in Biology

About Pliant Therapeutics, Inc.

pliantrx.com

Headquarters

South San Francisco, California, United States

Company Size

51-200 employees

Founded

2015

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Pliant Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery and development of integrin-based therapies. The company leverages its proprietary discovery platform to advance tissue-specific integrin programs targeting a range of diseases, including fibrotic conditions and oncology. Pliant's pipeline includes drug candidates such as PLN-101095 in oncology, with a broader mission to unlock safer and more effective therapies for patients through targeted integrin biology.