Pioneering Medicines: Principal Scientist / Associate Director , Non-Clinical Pharmacology

Flagship Pioneering, Inc.(1 month ago)

Cambridge, MAOnsiteFull TimeDirector$148,000 - $203,500Pharmacology

About this role

The Principal Scientist / Associate Director will serve as the nonclinical pharmacology lead for programs in inflammation, autoimmunity, and immuno-oncology, owning in vivo strategy from hit-to-lead through IND. The role partners across functions (Cell Biology, Translational Medicine, DMPK/QSP, Tox, TechOps) and works in a matrix environment to generate decision-quality data. The position manages an internal in vivo team and external CROs/consultants and evaluates new models and technologies to advance programs.

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Required Skills

Pharmacology Lead
In Vivo
Study Design
Disease Models
PD Biomarkers
PK/PD
Dose Translation
Model Development
Team Management
CRO Management

+5 more

Qualifications

About Flagship Pioneering, Inc.

flagshippioneering.com

Flagship Pioneering is a venture creation and investment firm that invents, builds, and funds early-stage companies in biotechnology, life sciences, and sustainability. Using an integrated model of in-house science, lab infrastructure, capital, and operational support, it spins out and scales breakthrough ventures — it has helped found more than 100 companies, including high-profile names such as Moderna. Flagship focuses on deep‑science innovation and long‑term partnerships to translate novel discoveries into transformative products for human health and the planet.