Principal Scientist, Analytical Development

Flagship Pioneering, Inc.(27 days ago)

Cambridge, MAOnsiteFull TimeSenior$163,000 - $214,500Analytical Development

About this role

The Principal Scientist will lead analytical development for novel lipid nanoparticles (LNPs) and nucleic acid cargos, driving method development, characterization, and control strategies from platform research through IND. The role partners with formulation, process development, and translational teams, manages external lab/CRO relationships, and supervises junior scientists while maintaining hands-on experimental involvement. This position supports establishing CQAs/CPPs and contributes to technical documentation and regulatory-ready analytical strategies.

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Required Skills

Analytical Development
Method Development
LNP Characterization
Nucleic Acid
DLS
HPLC
LC-MS
SEC
FFF-SEC-MALS
CE

+14 more

Qualifications

Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or Related Discipline (8+ years industry experience)
M.S. in Related Discipline (10+ years industry experience)

About Flagship Pioneering, Inc.

flagshippioneering.com

Flagship Pioneering is a venture creation and investment firm that invents, builds, and funds early-stage companies in biotechnology, life sciences, and sustainability. Using an integrated model of in-house science, lab infrastructure, capital, and operational support, it spins out and scales breakthrough ventures — it has helped found more than 100 companies, including high-profile names such as Moderna. Flagship focuses on deep‑science innovation and long‑term partnerships to translate novel discoveries into transformative products for human health and the planet.