Principal Scientist, In Vivo Pharmacology

Calico (1 month ago)

South San Francisco, CAOnsiteFull TimeSenior$198,000 - $207,000Drug Discovery

About this role

A Principal In Vivo Pharmacologist at Calico provides scientific leadership within the Translational Drug Discovery portfolio, focusing on neurodegenerative and oncology programs. The role centers on translating biological understanding into preclinical strategies and translational evidence to inform development decisions and IND-enabling plans. The position partners with internal teams and external collaborators to advance programs through proof-of-concept and PK/PD characterization.

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Required Skills

In Vivo
Pharmacodynamics
PK/PD
Model Development
Study Design
Data Analysis
Project Management
CRO Management
External Partnerships
Scientific Leadership

+4 more

Qualifications

Ph.D. in Pharmacology, Neuroscience, Tumor Biology, or Related Field

About Calico

calicolabs.com

Calico (Calico Life Sciences LLC) is an Alphabet-backed research and development company focused on understanding the biology of aging and translating that knowledge into interventions to extend healthy lifespan. The company combines large-scale biology, genetics, chemistry and computational approaches to discover targets, biomarkers and potential therapies for age-related diseases. Calico works through multi‑disciplinary teams and collaborations with academic and industry partners to move fundamental discoveries toward clinical impact.