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Principal Scientist, Translational Modeling & Decision Science at Flagship Pioneering, Inc. - ApplyBlast

Principal Scientist, Translational Modeling & Decision Science

Flagship Pioneering, Inc.

3 months ago

Cambridge, MA, United States

Onsite

Full Time

Senior

0 applicants

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About this role

This role involves building AI systems to accelerate translational decision-making across Flagship's therapeutic portfolio. The candidate will bridge the gap between technical capability and business impact by leveraging PI technologies to address translational challenges, delivering value through programs and business decisions while returning insights to improve the AI platform. Success requires reducing scientific uncertainty behind drug development and investment decisions through mechanistic modeling and quantitative analysis.

Responsibilities

Produce quantitative opinions across decision types and scenarios
Deliver translational predictions with stated confidence and boundary conditions
Carry insight between programs to flag relevant translational risks
Translate field discoveries into product requirements for AI teams
Set quality standards on engagements with rigorous evidence evaluation

Skills

Qualifications

PhD in Life SciencesPhD in Quantitative Life SciencesExpertise in Mechanistic ModelingProficiency in Python Scientific ComputingKnowledge of Physiology and Molecular Biology

About Flagship Pioneering, Inc.

flagshippioneering.com

Headquarters

Cambridge, Massachusetts, United States

Company Size

201-500 employees

Founded

2000

View Profile

Flagship Pioneering is a venture creation and investment firm that invents, builds, and funds early-stage companies in biotechnology, life sciences, and sustainability. Using an integrated model of in-house science, lab infrastructure, capital, and operational support, it spins out and scales breakthrough ventures — it has helped found more than 100 companies, including high-profile names such as Moderna. Flagship focuses on deep‑science innovation and long‑term partnerships to translate novel discoveries into transformative products for human health and the planet.