Principal Scientist

Denali Therapeutics is seeking a Principal Scientist to provide strategic technical leadership for late-phase and commercial analytical development of large molecule therapeutics. The role involves overseeing analytical method qualification, validation, and transfer activities at contract development and manufacturing organizations (CDMOs) while driving the implementation of analytical control strategies. This position requires hands-on laboratory execution, mentorship of junior colleagues, and collaboration with cross-functional teams to support accelerated CMC development and commercial timelines.