Project 8: Predicting microprotein functionality through evolutionary analysis

This position involves building and validating computational models to predict the functionality of recently evolved microproteins using evolutionary features and public genetic data. The role includes prioritizing candidate microproteins for functional validation, conducting CRISPR-Cas9 screens in cancer cell lines, and collaborating across the ORFeus network. The researcher will also complete a secondment at an industry partner to apply models to therapeutic applications.