Research Scientist

The Sankar Laboratory and the Department of Anatomy, Cell Biology & Physiology at Indiana University School of Medicine are seeking a highly motivated Research Scientist to lead studies within a newly funded NIH project investigating cell-intrinsic pain mechanisms in osteoarthritis (OA). This interdisciplinary project will use global and conditional knockout mouse models to investigate sensory neuron and joint cell-intrinsic roles of Ca2+/calmodulin-dependent protein kinase kinase 2 (CAMKK2) in OA pain using single-cell RNA sequencing and spatial transcriptomics of the joint. The project will also employ cutting-edge 3D light-sheet microscopy to map sensory neuron dynamics and inflammation during OA progression and mechanistic signaling studies in the dorsal root ganglion.