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Scientist at Nurix - ApplyBlast

Scientist

Nurix

2 months ago

3.9 on Glassdoor

Brisbane, California, United States

Onsite

Full Time

Senior

0 applicants

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About this role

Nurix Therapeutics is looking for a Scientist to lead bioanalytical strategies for degrader antibody conjugates (DACs), focusing on LC‑MS/MS and hybrid assay approaches to quantify and characterize complex bioconjugates in vitro and in vivo. The role will involve method development, qualification, and execution to support pharmacokinetic, pharmacodynamic, and biotransformation studies, and will collaborate closely with DMPK, proteomics, pharmacology, and chemistry teams.

Responsibilities

Lead development and qualification of DAC bioanalytical methods
Design and execute LC-MS/MS workflows for payload quantitation
Collaborate with cross-functional teams to interpret PK/PD data

Skills

Qualifications

Ph.D.M.S.

About Nurix

nurixtx.com

Headquarters

Brisbane, California, United States

Company Size

201-500 employees

Founded

2012

View Profile

Nurix Therapeutics is a clinical-stage biopharmaceutical company developing medicines that harness targeted protein degradation to treat cancer and autoimmune diseases. Using a proprietary platform that combines small-molecule degraders and Degradation Activating Compounds (DACs) to engage E3 ubiquitin ligases and the ubiquitin–proteasome system, Nurix aims to selectively remove disease-causing proteins. The company advances multiple discovery and development programs and collaborates with partners to translate its platform into novel therapies. Their mission, "Medicines to Outmatch Disease," guides efforts to create differentiated, targeted treatments.