Senior Scientist, Biophysics

Treeline Biosciences(26 days ago)

San Diego, CA, California, United StatesOnsiteFull TimeSenior$151,694 - $174,363Research & Development

About this role

Senior Scientist, Biophysics at Treeline Biosciences will design and implement biophysical strategies and assays to support small‑molecule hit identification, hit‑to‑lead, and lead optimization. The role partners closely with chemistry, biology, and lead discovery teams to characterize protein–small molecule interactions and uncover mechanisms of action. The scientist will provide expert interpretation of biophysical data and integrate those insights to drive program decisions toward development candidates.

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Required Skills

Biophysical Assays
Assay Development
SPR
DSF
MST
NMR
DLS
Protein Interactions
Mechanistic Analysis
Data Analysis

+6 more

Qualifications

PhD in Biophysics, Biochemistry, Chemistry or Chemical Biology
2-3 Years Postdoctoral Training
4+ Years Biotech/Pharma Experience

About Treeline Biosciences

treeline.bio

Treeline is a biotechnology company focused on engineering and controlling cell fate to enable next‑generation regenerative medicines and research tools. They combine synthetic biology, genetic payload design, and computational single‑cell analysis to create lineage‑targeted delivery platforms and programmable therapeutics that reprogram or repair tissues in vivo. Treeline partners with academic labs and biopharma to translate its platform into scalable treatments and discovery tools for degenerative and chronic diseases.