Senior Scientist, Medicinal Chemistry

Calico (1 month ago)

South San Francisco, CAOnsiteFull TimeSenior$166,000 - $191,000Medicinal Chemistry

About this role

Calico is seeking a Senior Scientist to join its Medicinal Chemistry team to design and synthesize novel small molecules and drive lead discovery across diverse therapeutic areas. The role requires directing chemistry efforts, managing external synthetic partners, and communicating results to cross-functional teams and senior leadership. The scientist will also contribute to patent applications and scientific publications while supporting project decision-making.

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Required Skills

Organic Chemistry
Medicinal Chemistry
Small Molecules
Drug Discovery
SBDD
Computational Chemistry
ADME
Lead Optimization
CRO Management
Team Leadership

+9 more

Qualifications

Ph.D. in Organic or Medicinal Chemistry
Postdoctoral Experience

About Calico

calicolabs.com

Calico (Calico Life Sciences LLC) is an Alphabet-backed research and development company focused on understanding the biology of aging and translating that knowledge into interventions to extend healthy lifespan. The company combines large-scale biology, genetics, chemistry and computational approaches to discover targets, biomarkers and potential therapies for age-related diseases. Calico works through multi‑disciplinary teams and collaborations with academic and industry partners to move fundamental discoveries toward clinical impact.