Senior / Staff Computational Scientist

Twist Bioscience(18 days ago)

HybridFull TimeSenior$173,000 - $200,000Scientific Computing

About this role

A Senior/Staff Computational Scientist at Twist Bioscience builds computational systems and analysis workflows that support antibody programs, producing explainable, versioned outputs used by scientists and operations teams. The role partners closely with wet-lab scientists, assay development, QC, software engineers, and ML teammates to scale solutions that improve triage, quality, and throughput. It is a hands-on builder position focused on delivering durable scientific software and data pipelines.

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Required Skills

Antibody Science
Python Programming
Data Analysis
Feature Engineering
Machine Learning
Bioinformatics
QC Frameworks
Software Engineering
Cloud Tooling
LIMS Integration

Qualifications

MS in Computational Biology or related field
PhD in Computational Biology or related field

About Twist Bioscience

twistbioscience.com

Twist Bioscience is a San Francisco–based synthetic biology company that developed a proprietary silicon‑based DNA synthesis platform to produce high‑quality synthetic DNA at scale. It offers gene synthesis, oligo pools and pooled libraries, NGS target‑enrichment and exome panels, variant libraries, and related synthetic DNA tools. Twist serves research, diagnostics, drug discovery and industrial biotech customers, emphasizing high throughput, accuracy, and scalable manufacturing to accelerate genetic engineering, sequencing, and therapeutic development.