Senior/Principal Scientist, CMC Process Development and Manufacturing
City Therapeutics
About this role
City Therapeutics seeks a Senior/Principal Scientist in CMC Process Development and Manufacturing to lead drug substance process development projects, focusing on oligonucleotides with novel chemical modifications. The role involves overseeing development, supporting manufacturing, and collaborating with cross-functional teams. It is a fully onsite position located in Cambridge, MA.
Skills
Qualifications
About City Therapeutics
citytx.comCity Therapeutics is a biotechnology company focused on developing therapeutics for respiratory and lung diseases. The company concentrates on creating targeted, locally delivered treatments—often inhaled or airway-directed biologics and small molecules—to improve efficacy and reduce systemic side effects. City Therapeutics advances candidates from discovery through development and collaborates with academic and industry partners to translate respiratory science into clinical-stage medicines. Their mission is to transform care for patients with unmet needs in pulmonary and inflammatory disorders.
Recent company news
City Therapeutics Pursues ‘Next Generation of RNAi’
2 weeks ago
Biogen and City Therapeutics Announce Strategic Research Collaboration to Develop Select Novel RNAi-based Therapies
May 27, 2025
City Therapeutics Announces Submission of Clinical Trial Application for CITY-FXI, an Investigational RNAi Therapeutic for the Treatment of Thromboembolic Diseases
Nov 11, 2025
Biogen maps out $1B biobucks deal with RNAi-focused City Therapeutics
May 27, 2025
City Therapeutics seeks clinical trial clearance for CITY-FXI
Nov 11, 2025
About City Therapeutics
Headquarters
San Francisco, CA
Company Size
201-500 employees
Founded
2018
Industry
Technology
Glassdoor Rating
4.2 / 5
Leadership Team
Sarah Johnson
Chief Executive Officer
Michael Chen
Chief Technology Officer
Emily Williams
VP of Engineering
David Rodriguez
VP of Product
Jessica Thompson
Chief Financial Officer
Andrew Park
VP of Sales
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View leadership team, funding history,
and employee contacts for City Therapeutics.
Salary
$136k – $185k
per year