Sr. Bioinformatics Scientist – cfDNA Technology Development

Personalis, Inc(18 days ago)

HybridFull TimeSenior$155,000 - $190,000Bioinformatics

About this role

The Bioinformatics Senior Scientist at Personalis will support development and clinical application of ultra-sensitive, tumor-informed whole-genome sequencing (WGS)-based liquid biopsy assays for precision oncology. The role partners with bioinformatics, software, laboratory, and clinical evidence teams to apply cell-free and solid-tumor genomics platforms to patient cohorts and advance genomics-based MRD and ctDNA products. The position contributes to product development, evidence generation, and scientific communication of results.

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Required Skills

Cancer Genomics
Somatic Mutation Detection
Liquid Biopsy
ctDNA Analysis
WGS
Python
R
Experimental Design
Data Modeling
Scientific Publishing

Qualifications

Ph.D. in Bioinformatics, Genomics, or Related Field

About Personalis, Inc

personalis.com

Personalis is a genomics company focused on transforming the active management of cancer through comprehensive tumor and immune profiling. They deliver high‑resolution sequencing assays and proprietary bioinformatics — including whole‑exome and transcriptome sequencing, immune repertoire and HLA typing, and neoantigen discovery — to generate clinically actionable insights. Their products and services support precision oncology and immunotherapy development, enabling biomarker discovery, patient stratification, monitoring, and companion‑diagnostic research for pharma, diagnostic labs, and academic centers. Personalis emphasizes validated laboratory workflows and scalable informatics to produce accurate, regulatory‑grade data that accelerate clinical trials and personalized treatment decisions.