Sr Scientist – Director, Lipid Nanoparticle (LNP) Design and Delivery

Profluent(1 month ago)

Emeryville, CA, California, United StatesOnsiteFull TimeDirector$152,000 - $225,000Research & Development

About this role

The Sr Scientist–Director will found and lead Profluent’s LNP Design & Delivery group, architecting a liver-directed LNP platform and advancing approaches for extrahepatic targeting. This role drives programmable gene‑editing programs from concept through in vivo proof‑of‑mechanism and toward clinical translation. The position sits at the intersection of AI-driven protein design, next‑generation gene editing, and delivery science and will collaborate across discovery, development, and external partners.

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Required Skills

LNP Design
Formulation
Optimization
Characterization
Microfluidics
Encapsulation
Purification
Analytical Methods
DLS Analysis
LC/MS

+16 more

Qualifications

PhD in Chemical Engineering
PhD in Bioengineering
PhD in Chemistry
PhD in Biomedical Engineering
PhD in Molecular Biology

About Profluent

profluent.bio

Profluent is a synthetic‑biology company that uses AI to “author new biology,” building a platform to design, optimize, and deliver engineered biological solutions. Their technology couples generative machine‑learning models with experimental workflows to accelerate discovery and develop applications across medicine, agriculture, and industrial biotech. Profluent partners with academic and industry collaborators to translate computational designs into validated products and scale deployment. The company positions itself at the intersection of biology and AI, staffed by interdisciplinary teams of scientists and engineers.