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Structural Biology Research Scientist at Guidehouse - ApplyBlast

Structural Biology Research Scientist

Guidehouse

4 months ago

3.2 on Glassdoor

Bethesda, MD

Onsite

Full Time

Senior

1 applicant

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About this role

A Structural Biology Research Scientist at Guidehouse supports the National Institute of Allergy and Infectious Diseases by designing viral protein constructs and optimizing expression systems. The role involves protein purification, conducting biophysical characterization, and preparing samples for cryo-electron microscopy to advance vaccine development. Candidates will collaborate on technical reporting and mentorship while operating sophisticated scientific instrumentation in an on-site setting.

Responsibilities

Design and generate expression constructs for viral proteins
Optimize protein expression systems in mammalian and insect cells
Purify proteins using affinity and ion exchange chromatography
Perform binding assays and biophysical characterization via SEC-MALS
Operate cyano-EM instruments and prepare vitrification samples

Skills

Qualifications

PhD in Structural BiologyPublic Trust ClearanceFederal Clearance EligibilityDoD Public TrustMicrosoft Office

About Guidehouse

guidehouse.com

Headquarters

Mclean, Virginia, United States

Company Size

10001+ employees

Founded

2018

View Profile

Guidehouse is a leading advisory firm that specializes in integrating commercial and public sector solutions to tackle complex challenges faced by clients. As a unique scaled advisory organization, it leverages insights from both government and commercial perspectives within its various industry segments. Guidehouse provides a range of technology and managed services, focusing on key sectors such as healthcare, financial services, defense, and infrastructure. The firm is recognized for its innovative approach to problem-solving, which combines strategic expertise with practical implementation.