Director, Oligo Team Lead
Manifold Bio
About this role
Manifold Bio is hiring an experienced drug development leader to define and execute the strategic vision for shuttled oligonucleotide therapeutics. The role will lead scientific staff and cross-functional drug discovery teams to discover, advance, and prepare tissue-targeted oligonucleotide candidates for clinical testing. The leader will also represent oligonucleotide expertise to partners, collaborators, and investors while shaping platform capabilities.
Skills
Qualifications
About Manifold Bio
manifold.bioManifold Bio is a biotech company that designs tissue-targeted medicines directly in vivo. They built a high-throughput in vivo (HTV) discovery engine that combines massively multiplexed in‑animal screening with AI‑powered design to discover and optimize targeted biologics. The platform enables engineering of tissue- and cell-type‑specific delivery modalities (for example, next‑generation brain shuttles) and supports strategic partnerships with pharma. Their approach aims to accelerate discovery and increase translational success for targeted biologic therapeutics.
Recent company news
Fierce BiotechRoche signs $2B pact to pilot Manifold Bio's shuttles to the brain
Nov 3, 2025
SynBioBetaManifold Bio Expands Leadership Team to Drive its AI + In Vivo Targeted Biologics Platform
Dec 16, 2025
Business WireManifold Bio Expands Leadership Team to Drive its AI + In Vivo Targeted Biologics Platform
Dec 15, 2025
BioPharma DiveRoche taps an AI specialist to craft new brain drugs
Nov 3, 2025
BioSpaceManifold Bio Announces Strategic Collaboration with Roche to Develop Multiple Next-Generation Brain Shuttles for Neurological Diseases
Nov 4, 2025
About Manifold Bio
Headquarters
San Francisco, CA
Company Size
201-500 employees
Founded
2018
Industry
Technology
Glassdoor Rating
4.2 / 5
Leadership Team
Sarah Johnson
Chief Executive Officer
Michael Chen
Chief Technology Officer
Emily Williams
VP of Engineering
David Rodriguez
VP of Product
Jessica Thompson
Chief Financial Officer
Andrew Park
VP of Sales
Unlock Company Insights
View leadership team, funding history,
and employee contacts for Manifold Bio.
Salary
$182k – $243k
per year
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