Drug Discovery, Project Team Leader

Calico (1 month ago)

South San Francisco, CAOnsiteFull TimeSenior$213,000 - $218,000Medicinal Chemistry

About this role

The Drug Discovery Project Team Leader at Calico will own and drive a small-molecule drug discovery project from hit identification through preclinical candidate nomination. The role sits within the Medicinal Chemistry team and requires deep expertise in medicinal and organic chemistry combined with strong project leadership and cross-functional collaboration. The leader will partner with internal and external teams to define target profiles, guide strategy, and communicate progress to senior leadership.

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Required Skills

Drug Discovery
Project Leadership
Medicinal Chemistry
Organic Chemistry
Synthetic Chemistry
ADME Characterization
Pharmacology
Structure-Based Design
Computational Chemistry
Multi-Parameter Optimization

+10 more

Qualifications

Ph.D. in Organic or Medicinal Chemistry
Postdoctoral Experience in Chemistry

About Calico

calicolabs.com

Calico (Calico Life Sciences LLC) is an Alphabet-backed research and development company focused on understanding the biology of aging and translating that knowledge into interventions to extend healthy lifespan. The company combines large-scale biology, genetics, chemistry and computational approaches to discover targets, biomarkers and potential therapies for age-related diseases. Calico works through multi‑disciplinary teams and collaborations with academic and industry partners to move fundamental discoveries toward clinical impact.