Principal Program Manager, Drug Discovery (Medicinal Chemistry and DMPK)

Calico (1 month ago)

HybridFull TimeSenior$188,000 - $200,000Drug Discovery

About this role

The Drug Discovery Principal Program Manager will drive advancement of Calico’s preclinical drug discovery pipeline from hit generation to clinical candidate nomination. The role coordinates complex, multidisciplinary projects executed largely through external CROs, ensuring on-time, on-budget delivery while maintaining scientific and compliance standards. The position serves as the central hub for communication, planning, and execution across internal and external stakeholders to support robust pipeline operations.

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Required Skills

CRO Management
Stakeholder Communication
Meeting Facilitation
Process Development
Data Transfer
Sample Logistics
Contract Management
Financial Tracking
Invoice Processing
Forecasting

+10 more

Qualifications

M.S. in Chemistry or Biology
Ph.D. in Chemistry or Biology
PMP Certification

About Calico

calicolabs.com

Calico (Calico Life Sciences LLC) is an Alphabet-backed research and development company focused on understanding the biology of aging and translating that knowledge into interventions to extend healthy lifespan. The company combines large-scale biology, genetics, chemistry and computational approaches to discover targets, biomarkers and potential therapies for age-related diseases. Calico works through multi‑disciplinary teams and collaborations with academic and industry partners to move fundamental discoveries toward clinical impact.