Senior Research Associate, Shuttled Oligo Therapeutics

Manifold Bio(1 month ago)

Boston, MAOnsiteFull TimeSenior$157,197 - $210,259 (estimated)Research

About this role

The Senior Research Associate will help build Manifold Bio’s oligonucleotide shuttling capabilities and support multiple oligo-based disease programs. The role enables experimental execution and contributes to development of molecular assay approaches used to evaluate PK/PD and therapeutic index. This position is part of a cross-functional team advancing the internal pipeline and establishing strategic partnerships for neuro and other applications.

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Required Skills

Cell Culture
Tissue Lysis
RNA/DNA Isolation
RT-qPCR
SDS-PAGE
Assay Development
Cell Assays
Cell-Free Assays
Lab Documentation
Data Analysis

+6 more

Qualifications

B.S. in Biology or related field
M.S. in Biology or related field

About Manifold Bio

manifold.bio

Manifold Bio is a biotech company that designs tissue-targeted medicines directly in vivo. They built a high-throughput in vivo (HTV) discovery engine that combines massively multiplexed in‑animal screening with AI‑powered design to discover and optimize targeted biologics. The platform enables engineering of tissue- and cell-type‑specific delivery modalities (for example, next‑generation brain shuttles) and supports strategic partnerships with pharma. Their approach aims to accelerate discovery and increase translational success for targeted biologic therapeutics.