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Senior Scientist, AI‑Enabled Structural Biology at Pfizer - ApplyBlast

Senior Scientist, AI‑Enabled Structural Biology

Pfizer

4 months ago

3.8 on Glassdoor

Groton, Connecticut, United States

Onsite

Full Time

Senior

0 applicants

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About this role

Pfizer is seeking a Senior Scientist in AI-Enabled Structural Biology to integrate advanced AI-guided protein design with cryo-electron microscopy for structure-based drug discovery. The role involves translating computational approaches into experimentally tractable solutions to accelerate the development of small molecules, biologics, and vaccine antigens. Candidates will lead iterative design-test-learn workflows and establish scalable data analysis pipelines within high-performance computing environments.

Responsibilities

Apply generative AI and computational protein design methodologies to engineer custom structural tools
Execute computational protein design workflows in high-performance computing environments
Lead end-to-end structural biology strategies including construct engineering and sample preparation
Develop automated pipelines for cryo-EM data processing and complex dataset analysis
Communicate scientific findings to drive data-informed decisions across discovery programs