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Development Asset Leader, Liver Franchise at Prime Medicine - ApplyBlast

Development Asset Leader, Liver Franchise

Prime Medicine

11 days ago

3.3 on Glassdoor

Cambridge, Massachusetts, United States

Hybrid

Full Time

Executive

0 applicants

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About this role

Prime Medicine is seeking an experienced Development Asset Leader to oversee in vivo LNP-delivered liver programs from early clinical development through licensure, starting with Wilson's Disease and Alpha-1 Antitrypsin Deficiency programs. The role involves leading a cross-functional team, managing integrated development plans, and scaling franchise-level leadership as the liver portfolio grows. The position requires strong strategic and operational expertise to drive clinical, regulatory, and commercial success.

Responsibilities

Own integrated development plan for liver assets from IND acceptance through regulatory approval
Lead cross-functional team spanning clinical, regulatory, CMC, and commercial functions
Deploy AI-enabled project management tooling to track timelines and risks

Skills

Qualifications

PhDMDPharmD

About Prime Medicine

primemedicine.com

Headquarters

Cambridge, Massachusetts, United States

Company Size

201-500 employees

Founded

2019

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Prime Medicine is a biotechnology company translating Prime Editing — a CRISPR-derived, “search-and-replace” genome‑editing technology that makes precise DNA changes without double‑strand breaks — into therapeutic medicines. The company develops optimized prime editors, guide RNAs and delivery systems to correct disease‑causing mutations across in vivo and ex vivo indications, with programs targeting genetic diseases in blood, liver and other tissues. Headquartered in Cambridge, MA and founded by leaders in genome editing, Prime Medicine is advancing a pipeline of discovery and preclinical programs and partnering to move therapies toward the clinic.