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Hardware Engineering Lead at Prolific Machines - ApplyBlast

Hardware Engineering Lead

Prolific Machines

12 days ago

Emeryville, California, United States

Onsite

Full Time

Director

0 applicants

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About this role

This hands-on engineering role focuses on building expertise in optical systems, robotic calibration, and the characterization of light interactions with biological systems. The position involves owning optical calibration processes, collaborating with cross-functional teams to understand light delivery and bioreactor conditions, and translating fundamental insights into reliable engineering solutions. Success requires strong systems thinking and the ability to operate effectively as both a scientist and an engineer.

Responsibilities

Own optical calibration processes and characterize hardware and biological optical properties
Collaborate with cross-functional teams to understand light delivery and bioreactor conditions
Translate company strategy into multi-year hardware roadmap and functional plans

Skills

Qualifications

BS, MS, or PhD in Mechanical, Electrical, Optical, Systems, or Biomedical Engineering

About Prolific Machines

prolific-machines.com

Headquarters

Emeryville, California, United States

Company Size

11-50 employees

Founded

2020

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Prolific Machines is a biotechnology company that pioneers light-controlled biomanufacturing using optogenetics to deliver dynamic, tunable control over protein expression in cell lines. Their platform integrates optogenetic cell line development, plug-and-play illumination hardware, and data-driven process optimization to achieve breakthrough yields — including an industry-record 21g/L titer — and superior quality control for complex biologics such as monoclonal antibodies, bispecifics, Fc fusions, cytokines, and viral vectors. The company partners with biotechs, pharmaceutical companies, and CDMOs through integrated development services, platform licensing, and GMP supply partnerships, all compatible with existing manufacturing infrastructure.