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Optical Calibration Engineer at Prolific Machines - ApplyBlast

Optical Calibration Engineer

Prolific Machines

1 month ago

Emeryville, California, United States

Onsite

Full Time

Senior

0 applicants

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About this role

Prolific Machines seeks an engineer to own and improve calibration systems for their optogenetic illumination hardware, develop experiments to characterize light delivery in bioreactors, and collaborate across multidisciplinary teams to link optical performance with biological outcomes. The role involves hands‑on optical system setup, data analysis, and translating findings into engineering recommendations within a dynamic startup environment.

Responsibilities

Own and improve calibration systems for illumination hardware
Develop and execute experiments to characterize light delivery in bioreactors
Collaborate across mechanical, electrical, firmware, data, biology, and bioprocess engineering teams

Skills

Qualifications

PhDMSBS

About Prolific Machines

prolific-machines.com

Headquarters

Emeryville, California, United States

Company Size

11-50 employees

Founded

2020

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Prolific Machines is a biotechnology company that pioneers light-controlled biomanufacturing using optogenetics to deliver dynamic, tunable control over protein expression in cell lines. Their platform integrates optogenetic cell line development, plug-and-play illumination hardware, and data-driven process optimization to achieve breakthrough yields — including an industry-record 21g/L titer — and superior quality control for complex biologics such as monoclonal antibodies, bispecifics, Fc fusions, cytokines, and viral vectors. The company partners with biotechs, pharmaceutical companies, and CDMOs through integrated development services, platform licensing, and GMP supply partnerships, all compatible with existing manufacturing infrastructure.